Successful treatment of type II pityriasis rubra pilaris with secukinumab
نویسندگان
چکیده
IL: interleukin PRP: pityriasis rubra pilaris TNF: tumor necrosis factor INTRODUCTION Pityriasis rubra pilaris (PRP) is a heterogeneous inflammatory skin disease characterized by follicular papules, orange palmoplantar keratoderma, and erythematous scaly patches with islands of skin sparing. Type II PRP is a rare, severe, chronic form of PRP presenting atypical features including long disease duration, palmoplantar keratoderma, ichthyosiform scaling, eczematous areas, and resistance to therapy. Here we propose a new alternative therapy for type II PRP with secukinumab, an antiinterleukin (IL)-17A monoclonal antibody.
منابع مشابه
A descriptive study of patients with Pityriasis Rubra Pilaris admitted in Sina Hospital in Hamadan in 1991-99
Background: Pityriasis rubra pilaris (PRP) is a rare skin disease characterized by follicular hyperkeratosis, perifollicular erythema with islands of normal skin scattered over the sheets of erythroderma, palmoplantar hyperkeratosis and pityriasis capitis with unknown etiology. Objective: This study has been done in order to determine the demographics, clinical and therapeutic aspects of PRP pa...
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